NICE Approve a New Treatment for Migraine

Written by AlisonFreemantle on Thursday 2nd November 2023

New class of drug – CGRP antagonist

In the newly published guidance, the National Institute of Health and Care Excellence (NICE) now recommend Vydura (rimegepant) as an option for the acute treatment of migraine with or without aura in adults.

Vydura (Pfizer) is indicated for both acute treatment and as a preventative treatment (for adults experiencing at least 4 migraine attacks per month).

It is available as a 75mg oral lysophille available from Alliance Healthcare.

 

Useful to know:

  • Second line treatment option after triptans
  • Side effects include nausea (mild - moderate)
  • Patients can use alongside NSAIDs, Paracetamol and Prochlorperazine but NOT with Triptans*
  • It does contain fish based gelatin
  • It provides treatment for up to 48 hrs (a second dose can be taken after 24 hrs in needed)

*If using for prevention of migraines (dose 1 tablet every 48 hrs) the patient may have a prescription for a triptan to use in case of acute breakthrough.

For more information: